Is IUI Process Painful?

- 23 Nov, 2022
- IVF and Infertility
- infertility
- Author: Prime IVF Centre / Dr. Nishi Singh
People who find conception challenging adopt various ways to get pregnant. One of the standard procedures most go for is Intra-Uterine Insemination or IUI.
Intrauterine insemination involves the direct implantation of sperm into the uterus to maximize the likelihood of pregnancy. The sperm have substantially easier access to the egg when using this process, which, in turn, increases conception success rates.
Well, many people have the misconception that the IUI procedure is painful. However, it is not the case. So, this article will explain how the process works and whether it is painful.
What is IUI?
IUI helps people address several male infertility-related issues. These can include low sperm counts or sperm that are too frail and slow to reach the fallopian tubes. So, the Intra-Uterine Insemination (IUI) procedure involves the insertion of sperm into the uterus, very close to the egg.
IUI is a non-invasive and cost-effective option compared to invasive fertility treatments. In addition, this procedure is significantly safer, more comfortable, and can improve fertility. Usually, the process takes no more than 15 minutes.
Is IUI Process Painful?
Well, whether IUI is painful has a partially positive answer. Usually, when the sperm is placed into the uterus for the first time, many individuals may experience severe discomfort. Some might even find it to be intolerable. But for most women, this procedure seldom hurts.
Patients do not need to be sedated or take painkillers during IUI because it is a minimally intrusive procedure. When you are anticipated to ovulate, IUI is done. It entails directly injecting sperm cells into the uterus to facilitate the sperm's proximity to the eggs. Thus, the process of fertilizing the egg is facilitated by cutting down on the sperm's journey time and distance to the uterus.
Some patients may feel minor pinching and mild cramping as the catheter is inserted through the cervix. But as the catheter goes into the cervix, you will mostly feel discomfort. Even doctors agree that patients suffer some discomfort throughout the operation. But if the sensation intensifies or becomes unpleasant, patients should immediately inform their doctor about their situation.
While having the treatment done, it is common to suffer cramps or minor bleeding. Ovulation itself might bring some cramps, especially if the patient is using an ovulation suppressant. But in most cases, the pain quickly subsides after the catheter is withdrawn. A small amount of bleeding might happen if the tube scratches the cervix, but this is not dangerous.
Thus, the statement that IUI is painful treatment may not be accurate for all, considering the factors involved in the procedure.
However, it must be noted that after the execution of the procedure, patients might suffer cramping if the uterus is somewhat inflamed.
How long does the IUI process take?
The IUI process is relatively quick and simple. And it is performed in a single session on the day of ovulation. The first step in the IUI process is ovulation induction, which is usually done with medication. The ovulation induction process may take about 7–14 days. But once ovulation is confirmed, the IUI procedure is scheduled.
Here it is important to know that The actual procedure of inserting sperm into the uterus usually takes only a few minutes. However, the entire process of preparing for IUI, including ovulation induction and monitoring, can take several days or even weeks.
While the IUI procedure is quick and simple, achieving pregnancy through IUI may take several cycles. Thus it is best to discuss with your doctor the duration of the IUI process and what to expect.

What to Expect During IUI Procedure?
IUI is paired with ovarian stimulation. Before the insemination operation, you are given fertility medications to facilitate ovulation. These medications do not make IUI painful treatment. However, you might encounter specific negative symptoms, like nausea, dizziness, and vision impairment.
Human Chorionic Gonadotropin (hCG), Follicle-Stimulating Hormone (FSH), and Clomiphene Citrate (Clomid) are occasionally used by doctors to aid in the process of ovaries' maturation and eventual release of one or more eggs. When more than one egg is produced during ovulation, the likelihood of becoming pregnant rises.
Besides, a sample of your partner's or the donor's semen is taken. Following collection, the sperm undergoes "sperm washing," which separates the healthiest sperm from the semen.
After cleaning the cervix and vagina with a gentle solution, the doctor introduces a small, flexible catheter into the vagina and guides it through the uterus. Then, the healthy sperm sample obtained is released using the catheter directly into the uterus. The cervix would stop sperm leakage from the uterus after the process.
To assess the success of the overall procedure, doctors often perform a pregnancy test after 14 days. Your doctor can advise a second IUI procedure if the results from the first pregnancy test are negative.
Who Can Get the IUI Treatment?
If the male partner's sperm count is poor or his sperm motility is insufficient, IUI is typically performed. In addition, IUI is recommended in the following situations.
- Pregnancy aspirations of single women
- Males with insufficient sperms
- Undiagnosed infertility
- Mucous issues in the cervical region or cervix
- Very mild endometriosis
- Those having trouble getting an erection or ejaculating
- Same-sex couples who want to get pregnant
- The couple does not want to pass on the male partner's genetic abnormalities to their unborn child.
Additionally, IUI may be a good option for treating recognized cervical conditions such as cervical mucus or scar tissue from prior surgeries. However, a doctor will not advise IUI for women with endometriosis, fallopian tube illness, or a history of pelvic infections.
Undiagnosed reproductive problems, including an imbalance in hormones or abnormalities in your uterus, may affect your ability to conceive.
Who Should Avoid IUI Treatment?
Doctors do not recommend IUI treatment for individuals with certain medical conditions. People with acute fallopian tube conditions and mild to severe endometriosis shouldn’t undergo this procedure.
Also, women with one or both fallopian tubes removed or obstructed cannot release eggs. Hence, they are not ideal candidates. Moreover, the treatment is not considered if the infertility is due to pelvic infections.
Besides, if the male has infertility issues or poor sperm production, the IUI procedure may not provide the desired result and is often not considered a suitable option.
Winding Up
When attempting to conceive naturally without success, it might be time to consider effective fertility treatments like Intra-Uterine Insemination or IUI. A significant number of people have seen positive results with this procedure. Most think IUI treatment is painful. The procedure does induce some discomfort. While the catheter is being inserted through the cervix, cramping might happen. But extreme pain among individuals is rare.
So, if you want to opt for IUI, Prime IVF Centre can be a great choice. Our doctors are well-trained and qualified to diagnose the underlying causes of the issue. They are equipped to perform IUI with minimal intrusion while ensuring you feel safe and comfortable during the entire process. Contact our experts to get more details regarding the process for a seamless experience.
FAQ's
1. Which is more painful, IUI or IVF?
IUI (Intrauterine Insemination) is generally considered to be less painful than IVF. IUI involves the insertion of sperm directly into the uterus, which may cause some mild discomfort, such as a pinching sensation and cramping when the catheter is inserted through the cervix.
On the other hand, IVF involves the retrieval of eggs and the transfer of embryos. This process often requires the use of anaesthesia and may cause some mild to moderate pain, cramping, and bloating. Some patients also report discomfort from the injection of hormones used during the IVF process.
2. Is IUI painful like HSG?
IUI is generally considered to be less painful than HSG (hysterosalpingography). HSG is a diagnostic procedure that involves injecting a contrast dye into the uterus and fallopian tubes to check for any blockages or abnormalities. This procedure can cause cramping and discomfort.
In comparison, IUI is a less invasive procedure, and the discomfort associated with it is usually mild. Patients may feel a mild pinching sensation when the catheter is introduced through the cervix. However, the level of pain varies from person to person, so it's best to talk to your doctor about what to expect during the procedure.
3. How long does IUl pain last?
IUI pain typically happens after the insemination process. However, it isn’t severe and doesn’t last long. Patients who experience slight bleeding or spotting generally experience pain that can last a maximum of one to two days.
4. Is IUl successful in the first attempt?
Intrauterine insemination is ideal for treating issues with unexplained fertility. Also, women with cervical mucus issues can benefit from the procedure. The success rate of IUI on the first attempt is 10-20% per cycle.
5. What is the disadvantage of IUI?
IUI has an array of benefits, but it comes with a few disadvantages, too, especially because it doesn’t address several fertility concerns. Compared to IVF, IUI has less success rate.
6. Is it hard to get pregnant with IUI?
IUI is often advised for women experiencing issues with blocked fallopian tubes or has reduced ovarian reserve. The success rate is subjective and will depend on the patient’s cause of infertility and the severity of the situation. If the blockage is close to the uterus, the success rate is around 38.1%, but if the blockage is close to the ovary, the success rate is 11.7%.